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The SURMOUNT-1 trial: Those on tirzepatide GIP GLP-1 (Mounjaro) saw up to 20.9% reduction [2]

Additionally, Que et al

This might be 2.5 mg weekly for some people

Inhibition of the hERG channel can cause fatal cardiac arrhythmias in humans ( 27 )

During fasting, hypoglycemia, or physiologic stress, glucagon increases hepatic glucose production through glycogenolysis and gluconeogenesis
