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Unfortunately, there is a paucity of biopsy-based pediatric MASLD studies, impeding an exact prescription of how much weight reduction should be achieved for histologic improvement in pediatric MASLD

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Spencer Nadolsky, an obesity doctor who has dug into this, keeps making both points at once: the loss is about what youd expect from any calorie deficit, and better imaging that separates real muscle from water and fat shows the scan numbers were overstated

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