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Misconception: Small weight loss is meaningless

[DOI] [PubMed] [Google Scholar] 269.Patti ME

Beyond these company-specific decisions, the broader industry is converging around a range of improvements, including continuous manufacturing (replacing slower, batch-by-batch production), aqueous peptide synthesis (which reduces solvent dependency), advanced digital monitoring, and site automation

Just how much of a challenge this posed can be gauged from the fact that Mutt's group needed 10km of porcine small intestine to obtain about 1mg of pure secretin (Rehfeld 2012)

Why the tablet is tricky Rybelsus only works properly when taken exactly as directed
