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Studies have shown how its use in mitochondria isolated from rodent brains and subjected to Ca 2+ -induced mPTP conferred protection from mitochondrial swelling and membrane depolarization 49 and prevented Cyt C release and cardiolipin peroxidation 54 via mPTP inhibition (Fig

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Semaglutide is a GLP-1 receptor agonist that enhances glucose-dependent insulin secretion, suppresses appetite via central nervous system pathways, and delays gastric emptying