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Clinical trials have demonstrated significant benefits of prescription GLP-1 agonists

Amylin is another hormone that promotes satiety and slows gastric emptying

Long-term administration of (Pro 3 )GIP to obese mice on an HFD was found to reduce body weight by about 8% compared to controls, without affecting food intake, and decrease casual blood glucose levels during the course of treatment and attenuated insulin levels during an oral glucose tolerance test [118]

For the secondary outcomes, the hazard ratios were below the null value for myocardial infarction, ischaemic stroke, cardiovascular mortality, heart failure, and all cause mortality, but with wide confidence intervals that included the null

Yet, the recent advances in GLP-1 receptor agonists such as Mounjaro weight loss injections, Wegovy, and Liraglutide, have found a relief for those suffering from PCOS, especially those struggling with weight and insulin resistance