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Clinical studies have revealed that semaglutide GLP-1 can result in substantial weight loss, with some participants experiencing an average reduction of 15% or more of their initial body weight

Olfactory dysfunction, including parosmia, has been associated with liraglutide use 46 , likely reflecting GLP-1R-mediated modulation of odor-evoked insulin secretion and foraging behaviors in the olfactory bulb 51,52

Therefore, basolateral LPL access to chylomicrons may be required

Traditional interventions, including lifestyle modifications, often fall short of achieving sustainable weight loss, ultimately leading to surgical interventions, which carry a significant burden and side effects

That said, maintenance isnt always straightforward