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The vascular hypometabolism hypothesis reframes dementia as a disorder of energy delivery, where chronic reductions in cerebral blood flow and glucose utilization precede and likely contribute to amyloid and tau pathology

The drug has a long half-life, which means it can be administered monthly or less frequently, giving the drug the potential to improve adherence and long-term weight control, according to Jay Bradner, executive vice president of research and development at Amgen

Rhett explained

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Patients taking warfarin can usually continue their therapy without significant issues