mechanism of action glp-1 agonist Receptor Agonists as Treatments for Type 2 Diabetes The protective role of GLP-1
Description
doi: 10.1038/nm.2513
Sixty-year-old Ravi* has lived with Type 2 diabetes for nearly 15 years
He notes that in humans GLP-1 reduces pancreatic inflammation and rarely increases amylase and lipase to more than the 3- fold increase which is needed to meet diagnostic criteria for pancreatitis
A Study of Orforglipron in Participants With Type 2 Diabetes (ACHIEVE-4)
While the full picture is still emerging, the breadth of these effects underscores why expectations for this drug class have soared
