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This also applies to other GLP-1 receptor agonists such as Dulaglutide, Liraglutide, and Tirzepatide, if any suspected adverse event occurs

GLP-1 and family history of thyroid cancer: Learn which thyroid cancer types contraindicate GLP-1 medications, understand FDA warnings about MTC and MEN 2, discover screening recommendations, and explore safe alternatives for high-risk patients.

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Its premise is an upstream intervention targeting substantial weight reduction to improve key risk factors with the aim to avoid potential downstream complications from multiple co-morbidities, e.g., hypertension, dyslipidaemia, heart failure, kidney disease, NAFLD/NASH or diabetes

Cases of early-onset colorectal cancer (EOCRC) have risen alarmingly since the 1990s, alongside a surge in metabolic diseases, particularly obesity and type 2 diabetes mellitus (T2DM), among young populations