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All DPP4i are more selective for DPP4 compared to other enzymes in the same family, such as FAP, DPP8, and DPP9, with selectivity ranging from less than 100fold for vildagliptin and saxagliptin to more than 14 000fold for alogliptin [66]

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Similarly, laxatives and diuretics can lead to dangerous electrolyte imbalances when combined with reduced food intake

Easy things, like having regular mealtimes, drinking water before meals, and resting enough, accumulate

A solution of compound of formula-3 a (4.45 gm) in THF (450 ml) was slowly added lot wise to the reaction mixture