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Monomeric GLP-1/GIP/Glucagon Triagonism Corrects Obesity, Hepatosteatosis, and Dyslipidemia in Female Mice

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However, slower gastric transit may: Reduce tolerance for large meals Increase early satiety Contribute to nausea in susceptible individuals The primary nutritional impact therefore arises from intake reduction rather than impaired absorption

Increasing before steady state means the body never fully adapts to one level before confronting the next