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Availability - Treatments like Ozempic are not available for prescription for weight loss as they are intended for patients with type-2 diabetes

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Treatment choices require individual tradeoffs The authors conclude: Treatment decisions for obesity should be individualized, balancing expected benefits, harms, treatment burden, costs, availability, and patient preferences. Researchers writing in a linked editorial said the comparison provides useful information for conversations between patients and clinicians as the number of obesity treatment options continues to expand

Preclinical studies have demonstrated that GLP-1 receptor agonists reduce neuroinflammation, reduce tau phosphorylation, reduce amyloid deposition, increase synaptic function, and improve memory formation

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