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The difference often depends on whether specific beneficial bacteria are supported during this transition Tirzepatide and Zepbound Gut Side Effects Tirzepatide is the active ingredient in Mounjaro, prescribed for type 2 diabetes, and Zepbound, prescribed for chronic weight management

Starting with a lower dose or adjusting the dosage with a healthcare provider may reduce digestive discomfort

Compounded versions, while sometimes well-intentioned, do not offer the same guarantees

Wallner M, Kolesnik E, Ablasser K, Khafaga M, Wakula P, Ljubojevic S, Thon-Gutschi EM, Sourij H, Kapl M, Edmunds NJ, Kuzmiski JB, Griffith DA, Knez I, Pieske B, von Lewinski D

Favorable Safety Profile AOD-9604 demonstrated a safety profile indistinguishable from placebo across over 900 human participants