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These comorbidities are interlinked via shared immunopathogenic mechanisms, notably chronic low-grade inflammation driven by Th1/Th17 cytokines such as TNF, IL-6, and IL-17

For some people, these medications can serve as a valuable adjunct to lifestyle change helping to enhance weight loss and metabolic outcomes when used appropriately
People with RLS may be prescribed certain medication, such as dopamine agonists, to ease their symptoms, but there are also many lifestyle changes that can be made to limit how uncomfortable RLS can be

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