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Reduction of TRT needs: Some men on testosterone replacement therapy (TRT) can reduce doses or discontinue entirely as natural production recovers with weight loss

And a recent experience microdosing the latest evolution has me rethinking what these weight loss drugs are actually doing in our bodies But lets back up

These are signs that the glucagon component is driving energy expenditure at a level that meaningfully contributes to the overall weight loss beyond what GLP-1 and GIP provide alone
The Pitfall of 'Eyeballing It': Inaccurate measurements of your diluent

Gut Health : A healthy gut microbiome is essential for optimal GLP-1 secretion