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505 In addition, LPS-treated mSOD1 G93A microglia caused microglial activation and released nitric oxide, which induced co-cultured motor neuron injury
Scientists spent a decade figuring out how to replicate that mutation pharmacologically
However, factors such as advanced aging, peripheral inflammation, and cerebral amyloid angiopathy can compromise the integrity of the BBB [182, 183]
That's the kind of connection that makes him feel supported, he says
