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However, prior to secretion the amino terminal is cleaved resulting in GLP-1 (7-36 amide) which is the major form in human plasma and is commonly referred to as GLP-1 (89)

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The GLP-1 and hormones article covers how semaglutide interacts with female hormone systems more broadly, which is relevant context for women with PCOS planning their postpartum path

Important safety considerations for transdermal patches: Avoid applying external heat (such as heating pads, hot water bottles, electric blankets, or prolonged sun exposure) to the patch area, as this may increase drug absorption and side effects Do not cut patches or apply additional adhesives unless specifically instructed to do so Wash hands thoroughly after handling patches to avoid transferring medication to eyes or mucous membranes For patients currently using licensed injectable GLP-1 receptor agonists, continue to follow the administration instructions provided in the PIL and by your healthcare team

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