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The authors of the study concluded that the GLP-1 receptor agonist lixisenatide had a three-point beneficial effect, when compared with placebo, in the change over a 12-month period from a baseline value of approximately 15 points on a 132-point scale measuring motor disability. The active arm improved 0.04 points in the lixisenatide group and worsened 3.04 points in the placebo group

Am J Physiol Gastrointest Liver Physiol 302 , G225235, (2012)

Pancreatitis risk requires monitoring Rare but serious

Some wont yet the research is moving faster than the textbooks

However, several unanswered questions remainnamely, whether GLP-1RAs, given their common gastrointestinal side-effects such as nausea, vomiting, and altered bowel habits, are safe and tolerable in patients with IBD