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In the mesolimbic system, GLP-1R activation has been shown to attenuate the rewarding effects of palatable food and addictive substances, indicating potential therapeutic applications for GLP-1R agonists in treating obesity and SUDs [19,20,21]
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For INS-1 832/3, agonists were added in HBSS (acute incubations) or complete medium (prolonged incubations), at 11 mM glucose, at the time of seeding into plates
Clean hands help prevent germs from getting on the medication or your injection site
Serum insulin was significantly lower at baseline and 52 weeks compared with screening for both groups, P 0.05 (Supplementary Figure 2)
