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Nevertheless, sustained weight loss through lifestyle modification remains the cornerstone of MASLD prevention and therapy

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Postnatal expression of ER tends to decline, but it remains present in microglia, oligodendrocytes, and specific brain regions, such as the hypothalamus and amygdala (Vargas et al., 2016)

If you want a grounded overview of currently used medicines in this area, Trim's guide to GLP-1 medicines in UK clinical practice is a useful starting point