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Description
The FDA prescribing information includes a boxed warning for thyroid C-cell tumors and notes that tirzepatide is not recommended for patients with severe gastrointestinal disease, including severe gastroparesis

1 Introduction Diabetes mellitus (DM), characterized by chronic hyperglycemia, is escalating globally, contributing to heightened morbidity and mortality from diabetic complications (Kirvalidze et al., 2022

Untreated anemia can exacerbate underlying cardiovascular issues

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This warning applies if someone has a personal or family history of medullary thyroid carcinoma or MEN-2
