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Following 6 weeks of HFD, all mice were switched to HFD supplemented with tamoxifen to induce cell GLP-1R knockdown and were maintained on this diet throughout study, resulting in a total duration of 8 weeks of HFD feeding before intervention, which results in impaired glucose tolerance, insulin secretion, and islet function, as previously established (2628)

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It brings together systems biology (how all parts of the body communicate), mitochondrial optimization ( improving the performance of your cell's power plants so they can create energy efficiently ), genetics (your inherited blueprint), exposomics the study of how toxins and the environment influence your genes and bioenergetic repair (restoring your body's energy production systems) into a single, personalized framework for precise healing and resilience