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However, the rheumatology community has not systematically investigated a role for GLP1-RAs in reducing the cardiovascular risk associated with inflammatory diseases
Gradual weight loss is key to sustainability and energy
it also has emotional ramifications
The triple agonist retatrutide (targeting GLP-1, GIP, and glucagon receptors) is in Phase 3 trials with early data showing up to 24% body weight reduction potentially exceeding both current agents
