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Whilst cold hands and feet are not listed as recognised adverse effects in the MHRA Summary of Product Characteristics, some patients report experiencing cold extremities during treatment

However, injection site reactions can result from many factors, including reconstitution technique, injection depth, and individual sensitivity, so attributing these solely to product quality would be premature without controlled testing

About 11% quit the trial because of side effects

Some are FDA-approved for weight loss and others are approved as treatments for diabetes but can be used off-label for weight loss

Losing even 5 to 10 percent of body weight quiets the inflammatory output of fat tissue