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Description
Efficacy, safety, and tolerability of oral semaglutide versus placebo added to insulin with or without Metformin in patients with type 2 diabetes: the PIONEER 8 trial
Add Variety : Switch up cardio routinestry swimming, cycling, or dance classes

Response rates were correspondingly lower: 66% of Contrave patients achieved 5% weight loss, and 36% reached 10% weight loss

In 2022, there was a shortage of GLP-1 medications, which in turn led the FDA to allow compounding pharmacies to sell the drugs

We thank Daniel Drucker and Anthony Gramolini (Toronto, Canada) and Gary Lopaschuk (Edmonton, Canada) for helpful discussions and Daniel Drucker for providing the Glp1r / mice
