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A mere 1% increase in GLP-1 utilization could drive a 5% increase in a self-insured employers drug spend, according to Prime data

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Mechanistically, liraglutide administration inhibited the upregulation of pain-related markers in the TNC, including calcitonin gene-related peptide (CGRP), c-fos, and components of the PI3K/Akt signaling pathway [94]
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