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Most important of these was Novo Nordisk demonstrating in a 17,000 patient five year clinical trial that Wegovy reduced the risk of major cardiovascular events (MACE) by 20%

Meta-Analysis of Prior Trials To develop a robust predictive model for the SOUL trial, historical data on semaglutide and its impact on MACE are needed

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Some people consider taking multivitamins while on GLP-1 medications to mitigate the effect, he said, although there isnt great data saying that taking a multivitamin is going to prevent hair loss. Rossi says some patients are in a chronic malnourished state while taking GLP-1s because the medication suppresses appetite