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Consistent with this, SEMA has been shown to induce browning of subcutaneous and epididymal WAT in obese male mice (Martins et al

In addition, emerging evidence suggests that ghrelin may influence neurocognitive processes involved in decision-making and reward evaluation, raising the possibility that altered ghrelin signalling contributes not only to metabolic dysregulation but also to the persistence of restrictive eating behaviours [162]

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