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This is one reason obesity is linked to higher RA disease activity, harder-to-reach remission, and lower response to treatment

Arillotta D, Floresta G, Guirguis A, Corkery JM, Catalani V, Martinotti G, et al
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Human trials are ongoing, but even modest effects in opioid use disorder could be clinically meaningful given the favorable safety profile of GLP-1 drugs compared with existing treatments
