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Research shows that high levels of stress can impair the bodies ability to fight infection leading to periodontal disease and bleeding gums as well as hypertension/high blood pressure

Mechanisms hypothesized to account for the effect of GLP-1 on glucagon secretion include: an indirect effect via the stimulation of somatostatin release from delta-cells or a direct effect on alfa-cells ( Gastrointestinal Tract Most GLP-1 is produced in the gastrointestinal (GI) tract and GLP-1R expression has classically been ascribed to myenteric plexus neurons throughout the gut ( Heart In the human and non-human primate heart, the GLP-1R is localized to myocytes of the sinoatrial (SA) node ( Lung and Kidney Our findings using non-human primate kidney tissue, as shown in Figure 6, demonstrate that GLP-1Rs are exclusively expressed in smooth muscle cells in the walls of arteries and arterioles, and studies with human tissue show the same ( Figure 6 Liver Hepatocytes do not express any measurable level of GLP-1Rs ( Thyroid As noted above, the thyroid gland is an organ where species-specific expression of the GLP-1R is evident