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Clinical trials have shown that patients on Zepbound can achieve average weight loss approaching that seen with some forms of bariatric surgery

Side effects improve significantly over time Second Natures research showed that side effects decrease substantially as the body adjusts to the medication: 3 Nausea dropped from 31.5% to 3.1% (semaglutide) and 27.8% to 10.5% (tirzepatide) by month 12 Fatigue dropped from 24.6% to 3.1% (semaglutide) and 21.5% to 8.1% (tirzepatide) by month 12 The proportion reporting no side effects increased significantly in both groups Hair loss: what the research shows Hair loss is often reported as a concern with weight-loss medications

If you notice changes in your voice or breathing, its smart to check in with your healthcare professional

Add tirzepatide's cleaner tolerability profile, as the 2nd receptor appears to blunt the nausea that pushed a meaningful share of patients off semaglutide before they ever reached an effective dose, she said

Surveys in which patients were asked about outcomes (and if they had an appendectomy, what they thought was the reason for the appendectomy) were available for 79% of the patients at 1 year, 57% at 2 years, 10% at 3 years, and 5% at 4 years (Fig
