mayo clinic glp 1 program Minute: Weight loss medications alone are not a quick fix Are GLP-1s everything we hoped

Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form

Participants switching from Zepbound to orforglipron were able to maintain prior weight loss with an average difference of 5.0 kg

Consistent data collection makes protocol adjustments more informed and outcomes more meaningful

Red Flags to Watch Pause the GLP-1 and call your prescriber if you have: Severe nausea or vomiting Dizziness or fainting spells Heart racing or chest discomfort Severe constipation or abdominal pain Practical Tips Hydrate, hydrate, hydrate

Fat is the largest and most expendable store, so most of the loss comes from fat