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Semaglutide's extended half-life of approximately one week allows for once-weekly subcutaneous administration (Ozempic and Wegovy) or daily oral dosing (Rybelsus)

Furthermore, CKD in patients with diabetes is globally the leading cause of end-stage kidney disease and leading to increased health care cost due to renal replacement therapy [4]

Supply and demand imbalance Prescription GLP-1 medications have experienced extraordinary demand

Use of fixed-dose combination (FDC) helps to improve therapy compliance and can provide optimum therapeutic benefits
