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The prevalence of AE under the use of GLP-1RAs is approximately 50%, depending on the type and dose of medication

In some cases, alternative treatments with fewer metabolic effects might be appropriate, or the timing of therapies could be optimised to minimise conflicting effects whilst maintaining therapeutic benefit

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Ozempic is not for treatment of type 1 diabetes mellitus

A prospective cohort study involving 32 T2DM patients on metformin monotherapy or metformin plus GLP-1RA illustrated that metformin plus GLP-1RA over 24 months of therapy was superior to metformin monotherapy (Rogliani et al