can you get addicted to semaglutide a GLP-1? Patients on Ozempic started reporting
Description
Connecting those anecdotal accounts with the fact that there are GLP-1 receptors in the brain in regions that modulate reward processing, and therefore might affect cravings, Al-Aly and his collaborators investigated whether GLP-1s could treat all substance use disorders
Phase 4: Steady state (Days 43+) Full adaptation

Published 2025

More than half of participants had type 2 diabetes and approximately three-quarters were living with obesity

Most dramatic before and after photos represent 6-12 months of consistent use, but changes start appearing much earlier
