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Most protocols recommend holding metformin on the morning of colonoscopy to minimize exposure during peak dehydration from bowel preparation

Metformin handles the insulin sensitivity piece, while GLP-1 drugs enhance pancreatic response and reduce appetite-driven calorie intake

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Enigk U, Breitfeld J, Schleinitz D, Dietrich K, Halbritter J, Fischer-Rosinsky A, et al

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