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Energy balance is regulated in the central nervous system command centerthe hypothalamus, specifically the arcuate nucleus, which is responsible for sensing energy status and controlling caloric intake and expenditure through orexigenic and anorexigenic neuropeptides [45, 46]
Conversion of proglucagon in pancreatic alpha cells: the major endproducts are glucagon and a single peptide, the major proglucagon fragment, that contains two glucagon-like sequences
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GLP-1 agonists can decrease absorption of birth control pills, which may lead to unplanned pregnancy
