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Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men

A 2022 study in JAMA Network Open also reported 5.1% weight loss at three months and 9.2% at six months among patients using doses at or below 1 mg weekly

And it will be the subject of the next article in this series: The GLP-1 Megatrend (2 of 4): The Biomarker Void That Will Break the Current Model.

Romeo S, Sanyal A, Valenti L (2020) Leveraging human genetics to identify potential new treatments for fatty liver disease
