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This effect is, at least in part, mediated through the inhibition of the nuclear factor-kappa B (NF-B) signaling pathway, which serves as a central regulator of inflammatory gene transcription

To report suspected adverse reactions to topiramate contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch

[1] [11] Cancer can also occur in the thyroid after spread from other locations, in which case it is not classified as thyroid cancer

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