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10.1152/physrev.00013.2014 22 SmeekensS
Safety and efficacy of 24 weeks of pemvidutide in metabolic dysfunction-associated steatotic liver disease: a randomized, controlled clinical trial
2019;9:e12323
We assessed whether a similar effect could be elicited by the primary metabolite of GLP-1 after DPP-4 cleavage, GLP-1 9-36 amide, as reported in mice
Clinical data shows semaglutide (Wegovy) produces 1022% weight loss over 68 weeks and sustains results long-term, while phentermine typically yields 57% weight loss over 12 weeks with rebound after discontinuation
