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While lixisenatide and exenatide demonstrate relatively rapid and direct action within central circuits, liraglutide and semaglutide may exert their effects more slowly or indirectly, potentially relying on longer systemic exposure, slow diffusion, or action through peripheralcentral pathways

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Der Wirkstoff kann Rezeptoragonisten im Krper aktivieren, was zur Kontrolle des Blutzuckerspiegels und zur Gewichtsabnahme beitrgt

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In combination with glimepiride, with or without metformin, the overall incidence of clinical adverse reactions with JANUVIA was higher than with placebo, in part related to a higher incidence of hypoglycemia (see Table 3)