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Prolonged GLP-1RAs therapy may exacerbate existing chronic inflammation in patients with T2DM, thereby potentially elevating their risk of pancreatic cancer

The side effect profiles are similar, and costs are comparable when considering available programs and compounded options

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To determine whether the signals share the same causal variant, we applied co-localization analysis 17 and found that the signals co-localize with high probability (BMI % versus nausea, H4 = 96.6%