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13 GLP-1 RA cardiovascular outcome trials 29 and head-to-head studies, 1529 with a follow-up range of 0.55.4 years, have documented that GLP-1 RAs increase heart rate by 0.15.7 b.p.m., with an average increase of 2.4 b.p.m

some patients maintain their weight loss, some regain weight, and some continue to lose weight

[6] [11] Precautions and warnings (not formal contraindications) include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, severe gastrointestinal disease, and previous pancreatitis

Going above this amount can cause diarrhea, which defeats the purpose when you are already dealing with GI discomfort

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