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NEW ORLEANS Once-daily orforglipron induced greater reductions in HbA1c than dapagliflozin and oral semaglutide for adults with type 2 diabetes, according to findings from the ACHIEVE-2 and ACHIEVE-3 trials

Although use of glucagon-like peptide-1 agonists for diabetes and weight loss has soared with indications now expanding into liver diseases, specifically metabolic dysfunction-associated steatohepatitis, the jury is still out on its benefit.With the recent FDA approval of Rezdiffra (resmetirom, Madrigal Pharmaceuticals) for the treatment for MASH, the question is whether (and how) GLP-1s will fit

Ford TC, Downey LA, Simpson T, McPhee G, Oliver C, Stough C