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These findings suggest a potential mechanism through which GLP-1 signaling may reduce glycation-related cellular stress
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Weight loss itself can improve sleep quality, self-esteem, and overall wellbeing, all of which may indirectly influence ADHD symptoms

Once pharmacological treatment is initiated and proves effective, it should not be arbitrarily time-limitedjust as we would not discontinue treatment for diabetes, hypertension, or other chronic diseases

Clinicians may consider this combination when metformin alone is not enough, when a person is already taking both ingredients separately, or when early combination therapy fits the overall care plan
