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Description
Retatrutide Peptide Dosing: What the Phase 2 Trial Reveals The landmark phase 2 trial, published in the New England Journal of Medicine in 2023, enrolled 338 adults with obesity across five dosing cohorts, including placebo

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A 16-year prospective cohort study to evaluate effects of long-term fluctuations in obesity indices of prediabetics on the incidence of future diabetes - PubMed

Quick answer: In the Phase 2 clinical trial (Jastreboff et al., 2023, New England Journal of Medicine ), retatrutide was given by once-weekly subcutaneous injection across a 112mg range
Establishes baseline tolerance
