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Systemic liraglutide administration activated LS GLP-1R neurons, and the knockdown of GLP-1Rs in the LS mitigated the anti-obesity effects of liraglutide

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Integrative solutions include: Therapy modalities like Cognitive Behavioral Therapy (CBT) or Emotional Freedom Technique (EFT) Mind-body practices such as yoga or meditation Nutrient deficiencies Because GLP-1 drugs slow digestion, theres a risk of reduced nutrient absorption, particularly of fat-soluble vitamins (A, D, E, and K)

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