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In the subsequent years, several observational studies have yielded conflicting results.4043 Notably, most of the available information is drawn from the subgroup of exendin-4-based drugs, which differ structurally from human GLP-1

Of note, the rate of premature treatment discontinuation due to AEs was comparable between genders, suggesting that the higher reported occurrence of GI AEs in women did not result in increased drug discontinuation

The study in the NEJM showing possible benefits of semaglutide in MASH patients with advanced inflammation and fibrosis is another exciting advance in our efforts to conquer this indolent, but deadly disease.

Can weight loss help kidney transplant eligibility
