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Contact your bariatric team, GP, or NHS 111 if you experience: Persistent vomiting that prevents adequate fluid or food intake note that prolonged vomiting carries a risk of thiamine (vitamin B1) deficiency , which requires prompt assessment and supplementation Signs of dehydration (dark urine, dizziness, dry mouth) Severe or worsening abdominal pain Difficulty swallowing (dysphagia) that does not resolve Symptoms of dumping syndrome that are frequent or severe Unexplained weight loss beyond expected post-operative targets Signs of nutritional deficiency, such as extreme fatigue, numbness or tingling in the hands and feet, or significant hair loss Seek emergency care (call 999 or attend A&E) if you notice: Chest pain or shortness of breath Signs of internal bleeding (vomiting blood or passing black, tarry stools) High fever with abdominal pain, which may indicate a leak or infection Persistent rapid heart rate (tachycardia) or shoulder-tip pain , which can be early signs of a post-operative leak and require urgent assessment Regarding sneezing specifically whilst it is generally benign, if it is accompanied by nasal congestion, post-nasal drip, or respiratory symptoms, an unrelated cause such as gustatory rhinitis, non-allergic rhinitis, or allergic rhinitis should be investigated

Current evidence supports the long-term safety of retatrutide when used under physician supervision

GLP-1RAs, through their anti-inflammatory effects, may play a role in decreasing the risk of PI

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Generics do not need to repeat the same clinical trials conducted by the original manufacturer, Novo Nordisk