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Model-based meta-analysis: an important tool for making quantitative decisions during drug development

Investigation of the cytokine and chemokine profiles in both the serum and CSF of patients with IIH has shown a significantly increased level of chemokine profiles in both the serum and CSF of patients with IIH has shown a significantly increased level of the chemokine CCL2 in the CSF of patients with IIH compared with controls, whereas CCL8, CCL7, and IL-1 were increased in the plasma in IIH, but not significantly (25)

however, there is currently no established pharmacotherapy available [109,110]

The improvements were also not solely explained by weight loss

Mondal S, et al